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ARL3 anticorps (C-Term)

L’anticorps Lapin Polyclonal anti-ARL3 a été validé pour WB, IF, FACS et ICC. Il convient pour détecter ARL3 dans des échantillons de Humain, Souris et Rat.
N° du produit ABIN7602850

Aperçu rapide pour ARL3 anticorps (C-Term) (ABIN7602850)

Antigène

Voir toutes ARL3 Anticorps
ARL3 (ADP-Ribosylation Factor-Like 3 (ARL3))

Reactivité

  • 53
  • 12
  • 12
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 47
  • 6
Lapin

Clonalité

  • 49
  • 4
Polyclonal

Conjugué

  • 22
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp ARL3 est non-conjugé

Application

  • 30
  • 19
  • 13
  • 13
  • 11
  • 6
  • 5
  • 3
  • 1
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)
  • Épitope

    • 15
    • 7
    • 7
    • 4
    • 4
    • 4
    • 3
    • 1
    C-Term

    Fonction

    Anti-ARL3 Antibody Picoband®

    Réactivité croisée (Details)

    No cross-reactivity with other proteins

    Attributs du produit

    Anti-ARL3 Antibody Picoband® (ABIN7602850). Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogène

    A synthetic peptide corresponding to a sequence at the C-terminus of human ARL3, identical to the related mouse and rat sequences.

    Isotype

    IgG
  • Indications d'application

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    1. Alkanderi, S., Molinari, E., Shaheen, R., Elmaghloob, Y., Stephen, L. A., Sammut, V., Ramsbottom, S. A., Srivastava, S., Cairns, G., Edwards, N., Rice, S. J., Ewida, N., Alhashem, A., White, K., Miles, C. G., Steel, D. H., Alkuraya, F. S., Ismail, S., Sayer, J. A. ARL3 mutations cause Joubert syndrome by disrupting ciliary protein composition. Am. J. Hum. Genet. 103: 612-620, 2018. 2. Cavenagh, M. M., Breiner, M., Schurmann, A., Rosenwald, A. G., Terui, T., Zhang, C., Randazzo, P. A., Adams, M., Joost, H. G., Kahn, R. A. ADP-ribosylation factor (ARF)-like 3, a new member of the ARF family of GTP-binding proteins cloned from human and rat tissues. J. Biol. Chem. 269: 18937-18942, 1994. 3. Grayson, C., Bartolini, F., Chapple, J. P., Willison, K. R., Bhamidipati, A., Lewis, S. A., Luthert, P. J., Hardcastle, A. J., Cowan, N. J., Cheetham, M. E. Localization in the human retina of the X-linked retinitis pigmentosa protein RP2, its homologue cofactor C and the RP2 interacting protein Arl3. Hum. Molec. Genet. 11: 3065-3074, 2002.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Antigène

    ARL3 (ADP-Ribosylation Factor-Like 3 (ARL3))

    Autre désignation

    ARL3

    Sujet

    Synonyms: ARL3, ARFL3, ADP-ribosylation factor-like protein 3

    Background: ADP-ribosylation factor-like protein 3 is a protein that in humans is encoded by the ARL3 gene. Enables GDP binding activity, GTP binding activity, and microtubule binding activity. Involved in several processes, including cilium assembly, protein localization to cilium, and small GTPase mediated signal transduction. Acts upstream of or within post-Golgi vesicle-mediated transport. Located in several cellular components, including microtubule cytoskeleton, midbody, and photoreceptor connecting cilium. Implicated in Joubert syndrome and retinitis pigmentosa 83.

    Poids moléculaire

    23 kDa

    ID gène

    403

    UniProt

    P36405
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